BACTERIA

AS

BIOFACTORIES

We use selected bacterial species and strains as natural biofactories for the production of nanomaterials, which is the core of our technology.

Bacteria are microscopic, single-celled prokaryotic organisms and are typically only a few micrometres in length, and have a wide variety of morphologies ranging from spheres to rods and spirals. These microscopic living forms were the first life forms to appear on Earth, and are present in most of its habitats making them a widely available source of input or raw materials.

  • Widely available
  • Self-improving

  • Self-sustained

  • Fast growing rate

RE- DESIGNING DETOXIFICATION

We use the natural mechanism of detoxification that bacterial use to resist stress from metal/metalloid ions that contaminate their environments. Detoxification involves the bacteria naturally removing or reducing the presence of toxic elements within their environment.

Bacteria are able to neutralize toxic ionic forms in their environment by using various inherent metabolic and regulatory pathways that we have tailored and adjusted to allow for the production of different nanomaterials.

  • Physicochemically-modified detoxification process

  • Quick and straighforward process

  • Environmentally-friendly approach
  • Cost-effective synthesis process

BACTERIAL

SYNTHESIZED

NANOPARTICLES

We have developed a novel method to purify, isolate, and partially modify nanomaterials as they are produced by different bacterial species or strains.

Different amounts of the nanostructures are easily transformed into a powder or an aqueous solution that can be readily applied to different platform and/or settings. Bacterial nanoparticles have an unique chemical identity that is dependent on the bacterial raw material employed for their production.

  • Unique chemical identity
  • Variable range of sizes
  • Versatility in storage
  • High stability over time

ANTIMICROBIAL

AGENTS

Due to their unique chemical identity, the nanoparticles can be used as broad or specific-spectrum antimicrobial agents through a mechanism of in situ inhibition of bacterial proliferation and controlling the spread of the bacterial disease without triggering a resistance to the treatment.

The nanoparticles can be applied to different settings with a dual effect: to prevent bacterial attachment and to disrupt and inhibit proliferation of the pathogens. To do so, the nanoparticles can be employed as sole therapeutics, nanocoatings, or can be embedded in organic and aqueous-like solvents for easy applicability. Besides, they do not elicit resistance to the treatment as happens with traditional antibiotics.

  • Selective or broad antimicrobial approach

  • Dual effect: prevention and treatment
  • No development of quick resistance
  • Environmentally-friendly antimicrobial